Joseph A Bauer Selected Research

nitrosocobalamin

12/2020	Nitric Oxide Inhibits NF-κB-mediated Survival Signaling: Possible Role in Overcoming TRAIL Resistance.
4/2014	A Stability-Indicating HPLC Method for the Determination of Nitrosylcobalamin (NO-Cbl), a Novel Vitamin B12 Analog.
9/2012	Pharmacokinetics of intravenous nitrosylcobalamin, an antitumor agent, in healthy Beagle dogs: a pilot study.
10/2010	Anti-tumor effects of nitrosylcobalamin against spontaneous tumors in dogs.
12/2007	Nitrosylcobalamin potentiates the anti-neoplastic effects of chemotherapeutic agents via suppression of survival signaling.
8/2006	Nitrosylcobalamin promotes cell death via S nitrosylation of Apo2L/TRAIL receptor DR4.
10/2003	Suppression of NF-kappa B survival signaling by nitrosylcobalamin sensitizes neoplasms to the anti-tumor effects of Apo2L/TRAIL.
7/2002	Effects of interferon beta on transcobalamin II-receptor expression and antitumor activity of nitrosylcobalamin.

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Joseph A Bauer Research Topics

Disease

13	Neoplasms (Cancer) 12/2020 - 03/2002
4	Carcinoma (Carcinomatosis) 01/2007 - 03/2002
3	Melanoma (Melanoma, Malignant) 12/2020 - 10/2003
1	COVID-19 01/2021
1	Meningioma (Meningiomas) 10/2010
1	Renal Cell Carcinoma (Grawitz Tumor) 08/2006
1	Necrosis 01/2005
1	Ovarian Neoplasms (Ovarian Cancer) 07/2002

Drug/Important Bio-Agent (IBA)

8	nitrosocobalaminIBA 12/2020 - 07/2002
8	nitrosylcobalaminIBA 12/2020 - 10/2003
8	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 02/2015 - 10/2003
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2020 - 10/2003
3	LigandsIBA 12/2020 - 10/2003
3	Cell Surface ReceptorsIBA 02/2015 - 10/2013
3	Transcobalamins (Transcobalamin II)IBA 02/2015 - 10/2013
3	Carrier Proteins (Binding Protein)IBA 02/2015 - 10/2013
3	Interferon-betaIBA 01/2007 - 03/2002
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2020 - 10/2003
2	AntibodiesIBA 12/2020 - 10/2013
2	NF-kappa B (NF-kB)IBA 12/2020 - 10/2003
2	Proteins (Proteins, Gene)FDA Link 02/2015 - 10/2013
2	inositol hexakisphosphate kinaseIBA 01/2005 - 03/2002
1	Antiviral Agents (Antivirals)IBA 01/2021
1	Anti-Infective Agents (Microbicides)IBA 01/2021
1	Nitric Oxide DonorsIBA 12/2020
1	Phosphotransferases (Kinase)IBA 12/2020
1	DNA (Deoxyribonucleic Acid)IBA 02/2015
1	Biomarkers (Surrogate Marker)IBA 02/2015
1	VitaminsIBA 10/2010
1	A 7 (A-7)IBA 10/2010
1	ProdrugsIBA 12/2007
1	Biotin (Vitamin H)FDA Link 08/2006
1	Caspase 8 (Caspase-8)IBA 10/2003
1	Caspase 3 (Caspase-3)IBA 10/2003
1	Interferon-alpha2bIBA 01/2003
1	Thalidomide (Thalomid)FDA Link 01/2003
1	Aligeron (AS 2)IBA 07/2002
1	Cytotoxins (Cytolysins)IBA 03/2002

Therapy/Procedure

5	Therapeutics 02/2015 - 03/2002
1	Aftercare (After-Treatment) 07/2002